教育经历：
1986年9月-1990年7月 华中农业大学 学士学位
1990年9月-1993年7月 华中农业大学 硕士学位
1993年9月-1996年7月 华东师范大学 博士学位
工作经历：
1996年7月-1998年8月 中国科学院水生生物研究所 博士后
1998年9月-今 华中师范大学生命科学学院，副教授、教授
2001年7月-2003年8月 法国巴黎居里研究所 博士后
2005年12月-2006年5月 澳大利亚昆士兰大学 访问学者；
主要研究领域：
1．动物（果蝇、鱼、虾）生殖与发育的分子调控机制；
2．水生经济动物（鱼、虾）增养殖学。
承担科研项目：
1. 国家自然科学基金项目（32170511）：沃尔巴克氏体感染对果蝇学习记忆的影响及机制研究，2022.1- 2025.12，主持。
2. 国家自然科学基金项目（31872288）：ocnus调控果蝇雄性生殖细胞发生的机制研究，2019.1- 2022.12，主持。
3. 国家自然科学基金项目（31672352）：Wolbachia对果蝇雄性生殖系统先天免疫的影响及其与生殖的关系，2017.1- 2020.12，主持。
4. 国家自然科学基金项目（31172155）：基于精子蛋白组学研究Wolbachia诱导果蝇CI的分子机制，2012.1- 2015.12，主持。
5. 国家自然科学基金项目（30970405）：Wolbachia感染对果蝇精子育性的影响，2010.1- 2012.12，主持。
6.国家自然科学基金项目（30671609）：雌核发育银鲫 Hira 基因的克隆及其功能分析，2007.1 - 2009.12,主持。
7.国家自然科学基金项目（30300035）：用功能获得性方法鉴定果蝇胚胎中囊胚过渡的调控因子，2004.1-2006.12，主持。
8. 教育部科学技术研究重点项目（109118）：从精子发生基因差异表达的角度研究Wolbachia诱导果蝇CI的分子机制，2009.1-2011.12，主持。
9. 武汉市学科带头人计划项目（201051730554）：克氏原螯虾健康养殖技术研究，2011.1-2013.12，主持。
10. 华中师范大学中央高校科研基本业务费（CCNU17SJ004）：克氏原螯虾性早熟机制的研究”，2017.1-2018.12，主持。
代表性论文：
1.Zhang HB, Cao Z, Qiao JX, Zhong ZQ, Pan CC, Liu C, Zhang LM*, Wang YF*. Metabolomics provide new insights into mechanisms of Wolbachia-induced paternal defects in Drosophila melanogaster. PLoS Pathogens, 2021, 17(8): e1009859.
2. Bi J, Wang YF*. The effect of the endosymbiont Wolbachia on the behavior of insect hosts. Insect Science, 2020, 27:846-858. （Review）
3. Biwot JC, Zhang HB, Liu C, Qiao JX, Yu XQ, Wang YF*. Wolbachia-induced expression of kenny gene in testes affects male fertility in Drosophila melanogaster. Insect Science, 2020，27：869–882.
4. Zheng Y, Shen W, Bi J, Chen MY, Wang RF, Ai H, Wang YF*. 2019. Small RNA analysis provides new insights into cytoplasmic incompatibility in Drosophila melanogaster induced by Wolbachia. Journal of Insect Physiology, 118: 103938.
5.Bi J#, Zheng Y#, Wang RF, Ai H, Haynes PR, Brownlie JC, Yu XQ, Wang YF*. 2019. Wolbachia infection may improve learning and memory capacity of Drosophila by altering host gene expression through miRNA. Insect Biochemistry and Molecular Biology, 106：47–54.
6. He Z, Zheng Y, Yu WJ, Fang Y, Bin Mao, Wang YF*. 2019. How do Wolbachia modify the Drosophila ovary? New evidences support the “titration-restitution” model for the mechanisms of Wolbachia-induced CI. BMC Genomics, 20: 608.
7. Kang PF, Mao B, Fan C, Wang YF*. 2019. Transcriptomic information from red swamp crayfish Procambarus clarkii ovary provides new insights into development of ovaries and embryos. Aquaculture, 505: 333–343.
8. Zheng Y#, Bi J#, Hou MY, Shen W, Zhang W, Ai H, Yu XQ, Wang YF*. 2018. Ocnus is essential for male germ cell development in Drosophila. Insect Molecular Biology, 27(5): 545-555.
9. Tan HY#, Shao GM#, Kang PF, Wang YF*. 2017. Full-length normalization subtractive hybridization analysis provides new insights into sexual precocity and ovarian development of red swamp crayfish Procambarus clarkii. Aquaculture, 468: 417-427.
10. Wu CH, Zong Q, Du AL, Zhang W, Yao HC, Yu XQ, Wang YF*. 2016. Knockdown of Dynamitin in testes significantly decreased male fertility in Drosophila melanogaster. Developmental Biology, 420: 79-89.
11.Yuan LL#, Chen X#, Zong Q#, Zhao T, Wang JL, Zheng Y, Zhang M, Wang Z, Brownlie JC, Yang F*, Wang YF*. 2015. Quantitative proteomic analyses of molecular mechanisms associated with cytoplasmic incompatibility in Drosophila melanogaster induced by Wolbachia. Journal of Proteome Research, 14: 3835-3847.
12. Liu C#, Wang J#, Zheng Y, Xiong EJ, Li JJ, Yuan LL, Yu XQ, Wang YF*. 2014. Wolbachia-induced paternal defect in Drosophila is likely by interaction with the juvenile hormone pathway. Insect Biochemistry and Molecular Biology, 49：49-58.
13. 王翠平，郑雅，郑金晶，王玉凤*. 2014. 黑腹果蝇Mst84Db敲降引起的父本缺陷类似Wolbachia诱导的细胞质不亲和. 昆虫学报， 57(3): 293-299.
14. Xia XF, Zheng JJ, Shao GM, Wang JL, Liu XS, Wang YF*. 2013. Cloning and functional analysis of glutathione peroxidase gene in red swamp crayfish Procambarus clarkii. Fish & Shellfish Immunology, 34: 1587-1595.
15. Zheng Y#, Wang JL#, Liu C, Wang CP, Walker T, Wang YF*. 2011. Differentially expressed profiles in the larval testes of Wolbachia infected and uninfected Drosophila. BMC Genomics, 12:595.
16. Zhao ZK, Li W, Wang MY, Zhou L, Wang JL, Wang YF*. 2011. The role of HIRA and maternal histones in sperm nucleus decondensation in the gibel carp and color crucian carp. Molecular reproduction and development, 78(2):139-147.
17. 王玉凤（主编）. 发育生物学（第二版）。北京：科学出版社，2021
18. 郭秋红，赵占克，王玉凤*，桂建芳. 2010. Hira基因产物在银鲫和彩鲫卵子发生过程中的动态变化. 水生生物学报， 34（3）：611-617
19. 彭宇，王玉凤*. 2009. Wolbachia感染显著提高果蝇嗅觉反应. 科学通报， 54: 596 - 602.
20. McMeniman CJ, Lane RV, Cass BN, Fong AWC, Sidhu M, Wang YF, O’Neill SL. 2009. The stable introduction of a life-shortening Wolbachia infection into the mosquito Aedes aegypti. Science, 323, 141-144.
（*通讯作者）
学术兼职:
1. 中国动物学会理事
2. 湖北省动物学会副理事长
Wang, Yu-Feng
Title： Professor
Office Address：5-305
Lab Address： 5-306
E-mail： yfengw(AT)ccnu.edu.cn
Resume:
Sep.1998.8-present:Associate professor,Professor,School of Life Sciences,Central China Normal University.
Dec.2005-May,2006:Academic visitor,School of Integrative Biology,The University of Queensland,Brisbane QLD 4072,Australia;
July,2001-Aug.2003:Post-doctor,UMR218, CNRs,Curie Institute-Section of Research,75248 Paris,France;
July,1996-Aug.1998:Post-doctor,Institute of Hydrobiology,Chinese Academy of Sciences;
Sep.1993-July,1996:Ph.D.,Dept.of Biology,East China Normal University;
Sep.1990-July,1993:M.Sc.,Dept.of Fisheries,Huazhong Agricultural University;
Sep.1986.9-July,1990:B.Sc.,Dept.of Fisheries,Huazhong Agricultural University.
Research Interestes:
1. Molecular regulatory mechanisms of reproduction and development in animals (Drosophila, fishes, shrimp);
2. Aquaculture technology of fishes and shrimps.
Research Grants：
1. National Nature Science Foundation of China（32170511）：Effects of Wolbachia infection on learning and memory capacity of Drosophila melanogaster and associated mechanisms. 2022- 2025.
2. National Nature Science Foundation of China（31872288）：Mechanisms of male germ cell development regulated by ocnus in Drosophila melanogaster. 2019- 2022
3. National Nature Science Foundation of China（No.: 31672352）：Effects of Wolbachia on innate immunity of reproductive system of Drosophila melanogaster and its association with reproduction. 2017- 2020.
4. National Nature Science Foundation of China (No.: 31172155): Molecular mechanism of CI induced by Wolbachia in Drosophila based on sperm proteomics. 2012-2015.
5. National Nature Science Foundation of China (No.: 30970405): Effect of Wolbachia infection on the fecundity of Drosophila. 2010-2012.
6. National Nature Science Foundation of China (No.: 30671609): Cloning and functional analysis of Hira gene in gynogenetic gibel carp. 2007-2009
7. National Nature Science Foundation of China (No.: 30300035): Identification of the factors involved in the regulation of mid-blastula-transition in Drosophila by gain-of-function. 2004-2006.
8. Key projects of science and technology of ministry of education of China（109118）：Study on the molecular mechanism of Wolbachia-induced CI in Drosophila melanogaster from the point of view of gene differential expression during spermatogenesis. 2009-2011.
Representative Peer-reviewed Publications:
1. Zhang HB, Cao Z, Qiao JX, Zhong ZQ, Pan CC, Liu C, Zhang LM*, Wang YF*. Metabolomics provide new insights into mechanisms of Wolbachia-induced paternal defects in Drosophila melanogaster. PLoS Pathogens, 2021, 17(8): e1009859.
2. Bi J, Wang YF*. The effect of the endosymbiont Wolbachia on the behavior of insect hosts. Insect Science, 2020, 27:846-858. （Review）
3. Biwot JC, Zhang HB, Liu C, Qiao JX, Yu XQ, Wang YF*. Wolbachia-induced expression of kenny gene in testes affects male fertility in Drosophila melanogaster. Insect Science, 2020，27：869–882.
4. Zheng Y, Shen W, Bi J, Chen MY, Wang RF, Ai H, Wang YF*. 2019. Small RNA analysis provides new insights into cytoplasmic incompatibility in Drosophila melanogaster induced by Wolbachia. Journal of Insect Physiology, 118: 103938.
5. Bi J#, Zheng Y#, Wang RF, Ai H, Haynes PR, Brownlie JC, Yu XQ, Wang YF*. 2019. Wolbachia infection may improve learning and memory capacity of Drosophila by altering host gene expression through miRNA. Insect Biochemistry and Molecular Biology, 106：47–54.
6. He Z, Zheng Y, Yu WJ, Fang Y, Bin Mao, Wang YF*. 2019. How do Wolbachia modify the Drosophila ovary? New evidences support the “titration-restitution” model for the mechanisms of Wolbachia-induced CI. BMC Genomics, 20: 608.
7. Kang PF, Mao B, Fan C, Wang YF*. 2019. Transcriptomic information from red swamp crayfish Procambarus clarkii ovary provides new insights into development of ovaries and embryos. Aquaculture, 505: 333–343.
8. Zheng Y#, Bi J#, Hou MY, Shen W, Zhang W, Ai H, Yu XQ, Wang YF*. 2018. Ocnus is essential for male germ cell development in Drosophila. Insect Molecular Biology, 27(5): 545-555.
9. Tan HY#, Shao GM#, Kang PF, Wang YF*. 2017. Full-length normalization subtractive hybridization analysis provides new insights into sexual precocity and ovarian development of red swamp crayfish Procambarus clarkii. Aquaculture, 468: 417-427.
10. Wu CH, Zong Q, Du AL, Zhang W, Yao HC, Yu XQ, Wang YF*. 2016. Knockdown of Dynamitin in testes significantly decreased male fertility in Drosophila melanogaster. Developmental Biology, 420: 79-89.
11. Yuan LL#, Chen X#, Zong Q#, Zhao T, Wang JL, Zheng Y, Zhang M, Wang Z, Brownlie JC, Yang F*, Wang YF*. 2015. Quantitative proteomic analyses of molecular mechanisms associated with cytoplasmic incompatibility in Drosophila melanogaster induced by Wolbachia. Journal of Proteome Research, 14: 3835-3847.
12. Liu C#, Wang J#, Zheng Y, Xiong EJ, Li JJ, Yuan LL, Yu XQ, Wang YF*. 2014. Wolbachia-induced paternal defect in Drosophila is likely by interaction with the juvenile hormone pathway. Insect Biochemistry and Molecular Biology, 49：49-58.
13. Wang CP, Zheng Y, Zheng JJ, Wang YF*. 2014. Paternal effects caused by the knockdown of Mst84Db mimic cytoplasmic incompatibility induced by Wolbachia in Drosophila melanogaster. Acta Entomologica Sinic， 57(3): 293-299.
14. Xia XF, Zheng JJ, Shao GM, Wang JL, Liu XS, Wang YF*. 2013. Cloning and functional analysis of glutathione peroxidase gene in red swamp crayfish Procambarus clarkii. Fish & Shellfish Immunology, 34: 1587-1595.
15. Zheng Y#, Wang JL#, Liu C, Wang CP, Walker T, Wang YF*. 2011. Differentially expressed profiles in the larval testes of Wolbachia infected and uninfected Drosophila. BMC Genomics, 12:595.
16. Zhao ZK, Li W, Wang MY, Zhou L, Wang JL, Wang YF*. 2011. The role of HIRA and maternal histones in sperm nucleus decondensation in the gibel carp and color crucian carp. Molecular reproduction and development, 78(2):139-147.
17. Wang YF（chief editor）. Developmental Biology (2nd edition). Beijing：Science Press，2021.
18. Guo QH，Zhao ZK，Wang YF*，Gui JF. 2010. Differential expression of Hira RNA and protein during oogenesis in gynogenetic and gonochoristic crucian carps. Acta Hydrobiologica Sinica， 34（3）：611-617
19. Peng Y，Wang YF*. Infection of Wolbachia may improve the olfactory response of Drosophila. Chinese Science Bulletin，2009， 54(8): 1369- 1375.
20. McMeniman CJ, Lane RV, Cass BN, Fong AWC, Sidhu M, Wang YF, O’Neill SL. 2009. The stable introduction of a life-shortening Wolbachia infection into the mosquito Aedes aegypti. Science, 323, 141-144.
（*Corresponding author）