教育经历:
1996年9月-2000年1月 中国科学院水生生物研究所 博士学位
1988年9月-1991年7月 西北农业大学 硕士学位
1981年9月-1985年7月 西北农学院 学士学位
工作经历:
2004年5月-至今 华中师范大学生命科学学院副教授、教授
2005年11月-2007年11月日本国立基础生物学研究所外国人特别研究员
2002年1月-2004年5月新加坡国立大学生物系Research Fellow
2000年7月-2004年5月湖北省农业科学院生物技术研究所副研究员
1993年1月-2000年7月湖北省农业科学院畜牧兽医研究所助理研究员、副研究员
1991年7月-1992年12月陕西省农业科学院科技情报研究所助理研究员
1985年7月-1988年8月陕西省商洛师范专科学校农学系助教
荣誉或奖励:
1999年 猪胚胎细胞核移植研究获湖北省科技进步三等奖
主要研究领域:
-鱼类生长与发育
-鱼类分子免疫
-鱼类性别分化与生殖
承担科研项目:
1.国家自然科学基金面上项目(31672284):Prdm1与Prmt5、Mep50的相互作用及其在鱼类先天免疫中的作用,2017.1-2020.12,主持。
2.国家自然科学基金面上项目(31272645 ):Prmt5在鱼类胚胎和生殖细胞发育中的作用机理研究,2013.1-2016.12,主持。
3.国家自然科学基金主任基金项目(31140053):Prmt5在青鳉生殖细胞发生及其干细胞维持中的作用机制研究,2012.1-2012.12,主持。
4.教育部科学技术研究重点项目:从精子发生基因差异表达的角度研究Wolbachia诱导果蝇CI的分子机制,2009.1-2011.12,参加。
5.教育部留学回国人员科研启动基金项目:稀有鮈鲫肌肉生长抑制素基因克隆及其表达调控,2005.1-2007.12,主持。
代表性论文:
1. Wentao Hong#, Meng Zhang#, Fengbang Wang, Zhunjie Li, Zhenyu Li, Jinbo Wei, Maoyong Song*, Yun Qian, Shaochen Pang, Ling Wang, Haobin Zhao*, Mengxi Cao*, Jianbo Shi, and Yong Liang.2024. Special Distribution of Nanoplastics in the Central Nervous System of Zebrafish during Early Development. ACS Nano, 18(27): 17509-17520. DOI: 10.1021/acsnano.4c00625.
2. Shi Duan, Qing Yang, Fan Wu, Zhenyu Li, Wentao Hong, Mengxi Cao, Xinhua Chen, Xueping Zhong, Qingchun Zhou, Haobin Zhao*. 2024. Maternal methylosome protein 50 is essential for embryonic development in medaka Oryzias latipes. The Journal of Experimental Zoology – A (JEZ-A): ecological and integrative physiology, 341(7): 798-810. https://doi.org/10.1002/jez.2824
3. Qiting Yao, Qing Yang, Zhenyu Li, Fan Wu, Shi Duan, Mengxi Cao, Xinhua Chen, Xueping Zhong, Qingchun Zhou, Haobin Zhao*. 2024. Methylosome protein 50 is necessary for oogenesis in medaka. Comparative Biochemistry and Physiology Part D: Genomics and Proteomics, 50:101220. https://doi.org/10.1016/j.cbd.2024.101220
4. Yao Q, Duan S, Yang Q, Ma X, Li Z, Wu K, Chang P, Cao M, Chen X, Wang Z, Zhong X, Zhou Q, Zhao H*.2023 Mar. Mep50 is essential for embryonic development in medaka fish. Gene, 868:147387. doi: 10.1016/j.gene.2023.147387.
5.Liang, X.; Duan, S.; Yang, Q.; Ma, X.; Li, Z.; Yao, Q.; Wu, K.; Chang, P.; Feng, G.; Hong,W.; et al. Protein Arginine Methyltransferase 5 Is Necessary for Embryonic Development in Medaka Oryzias latipes. Fishes 2023, 8, 19. https://doi.org/10.3390/fishes8010019
6.Md. Abdulla Al Hafiz, Xiaoting Liang, Qiting Yao, Hao Shen, Emile Nibona, Bing Wang, Zequn Wang, Xueping Zhong, Qingchun Zhou, Haobin Zhao*. 2022. Influence of dietary cholesterol on growth performance, fat accumulation, and expression of OlApoA-I with response to immune stimuli in medaka (Oryzias latipes). Inland Water Biology, 15, (5): 674–683.
7.Nibona E, Niyonkuru C, Liang X, Yao Q, Zhao H*. 2021. Essential roles of Prmt5-Mep50 complex formation and cancer therapy. Russ J Dev Biol, 52:344–353.
8.Ke X, Zhang R, Yao Q, Duan S, Hong W, Cao M, Zhou Q, Zhong X, Zhao H*. 2021. Alternative splicing of medaka bcl6aa and its repression by Prdm1a and Prdm1b. Fish Physiol Biochem, 47:1229–1242.
9.Shen H, Nibona E, Xu G, Al Hafiz MA, Ke X, Liang X, Yao Q, Zhong X, Zhou Q, Zhao H*. 2020. Identification, expression pattern, and immune response of Tim-1 and Tim-4 in embryos and adult medaka (Oryzias latipes). J Exp Zool B Mol Dev Evol, 334:235–244.
10.Shen H, Zhang X, Al Hafiz MA, Liang X, Yao Q, Guo M, Xu G, Zhong X, Zhou Q, Zhao H *. 2020. The proteins interacting with Prmt5 in medaka (Oryzias latipes) identified by yeast two-hybridization. Protein Peptide Lett, 27: 971–978.
11.Xu G, Shen H, Nibona E, Wu K, Ke X, Al Hafiz MA, Liang X, Zhong X, Zhou Q, Qi C, Zhao H*. 2019. Fundc1 is necessary for proper body axis formation during embryogenesis in zebrafish. Sci Rep,| 9:18910. https://doi.org/10.1038/s41598-019-55415-0
12.Nibona E, Xu G, Wu K, Shen H, Zhang R, Ke X, Al Hafiz A, Wang Z, Qi C, Zhao H*. 2019. Identification, characterization, expression profiles of OlHavcr2 in medaka (Oryzias latipes). Gen Comp Endocrinol, 277:30–37.
13.Zhang R, Ke X, Wu K, Shen H, Nibona E, Al Hafiz A, Liang X, Ye W, Zhou Q, Zhong X, Zhao H*. 2019. Expression of the alternative splicing variants of bcl6b in medaka Oryzias latipes. Comp Biochem Physiol Part B Biochem Mol Biol, 227:83–89.
14.Zhang R, Wu K, Ke X, Zhang X, Xu G, Shen H, Nibona E, Al Hafiz A, Liang X, Wang Z, Qi C, Zhou Q, Zhong X, Zhao H*. 2019. Bcl6aa and bcl6ab are ubiquitously expressed and are inducible by lipopolysaccharide and polyI:C in adult tissues of medaka Oryzias latipes. J Exp Zool Part B Mol Dev Evol, 332:17–25.
15.Cheng N, Guo M, Chang P, Zhang X, Zhang R, Qi C, Zhong X, Zhou Q, Zhao H*. 2016. Expression of mep50 in adult and embryos of medaka fish (Oryzias latipes). Fish Physiol Biochem, 42:1053–1061.