教育及工作背景:
2001.9-2005.7 河南师范大学生命科学学院、生物技术专业、理学学士
2005.9-2012.7 中国科学院北京基因组研究所、生物化学与分子生物学专业、理学博士
2012.9-2021.4 约翰斯·霍普金斯大学医学院、药学与分子科学系、博士后/RA
2021.6- 至今 华中师范大学生命科学学院、研究员
荣誉奖励
湖北省高层次人才支持计划(创新)项目(2022年)
武汉市“武汉英才”优秀青年人才(2021年)
主要研究领域:
1. 蛋白质互作筛选及其功能研究
2. DNA表观修饰阅读蛋白筛选及其功能研究
3. 生物大分子检测
招生招聘:
热忱欢迎生物化学与分子生物学、生物技术等相关专业的同学报考加盟。
代表性论文:
发表文章 (*标识为共同一作):
1.Ahmadi AR*, Song G*, Gao T*, Ma J, Han X, Hu MW, Cameron AM, Wesson RN, Philosophe B, Ottmann S, King E, Gurakar A, Qi L, Peiffer B, Burdick J, Anders R, Zhou Z, Lu H, Feng D, Chen CS, Qian J, Gao B, Zhu H, Sun Z. Discovery and characterization of cross-reactive intrahepatic antibodies in severe alcoholic hepatitis. Elife. 2023 Dec 6;12:RP86678.
2.Liu C*, Song G*, Yan S, He Y, Hu C, Hou Y, Wen X, Li L, Zhang F, Zhu H, Li Y. Identification of Anti-SNRPA as a Novel Serological Biomarker for Systemic Sclerosis Diagnosis. J Proteome Res. 2023 Oct 6;22(10):3254-3263.
3. Song, G.*, Wang, G.*, Luo, X.*, Cheng, Y., Song, Q., Wan, J., Moore, C., Song, H., Jin, P., Qian, J., and Zhu, H. (2021) An all-to-all approach to the identification of sequence-specific readers for epigenetic DNA modifications on cytosine. Nature Communications 2021 Feb 4;12(1):795.
4. Song, G.*, Lee, E.*, Pan, J.*, Xu, M.*, Rho, H., Cheng, Y., Whitt, N., Yang, S., Kouznetsova, J., Klumpp-Thomas, C., Michael, S., Moore, C., Yoon, K., Christian, K., Simeonov, A., Huang, W., Xia, M., Huang, R., Lal-Nag, M., Tang, H., Zheng, W., Qian, J., Song, H., Ming, G., and Zhu, H. (2021) An Integrated Systems Biology Approach 1 Identifies the Proteasome as a Critical Host Machinery for ZIKV and DENV Replication. Genomics, Proteomics & Bioinformatics. Volume 19, Issue 1, February 2021, Pages 108-122
5. Wen, X.*, Song, G.*, Hu, C.*, Pan, J., Wu, Z., Li, L., Liu, C., Tian, X., Zhang, F., Qian, J., Zhu, H., and Li, Y. (2021) Identification of novel serological autoantibodies in Takayasu arteritis patients using HuProt arrays. Molecular & Cellular Proteomics. 2021; 20:100036. doi: 10.1074/mcp.RA120.002119
6. Song, G.*, Chen, L.*, Zhang, B., Song, Q., Yu, Y., Moore, C., Wang, T., Shih, I., Zhang, H., Chan, D., Zhang, Z., and Zhu, H. (2019) Proteome-wide Tyrosine Phosphorylation Analysis Reveals Dysregulated Signaling Pathways in Ovarian Tumors. Molecular & Cellular Proteomics : MCP 18, 448-460
7. Liu, L.*, Li, T.*, Song, G.*, He, Q., Yin, Y., Lu, J., Bi, X., Wang, K., Luo, S., Chen, Y., Yang, Y., Sun, B., Yang, Y., Wu, J., Zhu, H., and Shen, X. (2019) Insight into novel RNA-binding activities via large-scale analysis of lncRNA-bound proteome and IDH1-bound transcriptome. Nucleic Acids Research 47, 2244-2262
8. Song, G.*, Rho, H.*, Pan, J.*, Ramos, P., Yoon, K., Medina, F., Lee, E. M., Eichinger, D., Ming, G., Munoz-Jordan, J., Tang, H., Pino, I., Song, H., Qian, J., and Zhu, H. (2018) Multiplexed Biomarker Panels Discriminate Zika and Dengue Virus Infection in Humans. Molecular & Cellular Proteomics : MCP 17, 349-356
9. Yoon, K., Song, G., Qian, X., Pan, J., Xu, D., Rho, H., Kim, N., Habela, C., Zheng, L., Jacob, F., Zhang, F., Lee, E., Huang, W., Ringeling, F., Vissers, C., Li, C., Yuan, L., Kang, K., Kim, S., Yeo, J., Cheng, Y., Liu, S., Wen, Z., Qin, C., Wu, Q., Christian, K., Tang, H., Jin, P., Xu, Z., Qian, J., Zhu, H., Song, H., and Ming, G. (2017) Zika-Virus-Encoded NS2A Disrupts Mammalian Cortical Neurogenesis by Degrading Adherens Junction Proteins. Cell Stem Cell 21, 349-358 e346
10. Pan, J.*, Song, G.*, Chen, D.*, Li, Y., Liu, S., Hu, S., Rosa, C., Eichinger, D., Pino, I., Zhu, H., Qian, J., and Huang, Y. (2017) Identification of Serological Biomarkers for Early Diagnosis of Lung Cancer Using a Protein Array-Based Approach. Molecular & Cellular Proteomics: MCP 16, 2069-2078
11. Hu, C., Pan, J., Song, G., Wen, X., Wu, Z., Chen, S., Mo, W., Zhang, F., Qian, J., Zhu, H., and Li, Y. (2017) Identification of Novel Biomarkers for Behcet Disease Diagnosis Using Human Proteome Microarray Approach. Molecular & cellular proteomics : MCP 16, 147-156
12. Song, G., Neiswinger, J., and Zhu, H. (2016) Characterization of RNA-Binding Proteins Using Protein Microarrays. Cold Spring Harbor Protocols 2016
13. Pham, X., Song, G., Lao, S., Goff, L., Zhu, H., Valle, D., and Avramopoulos, D. (2016) The DPYSL2 gene connects mTOR and schizophrenia. Translational psychiatry 6, e933
14. Yin, Y., Yan, P., Lu, J., Song, G., Zhu, Y., Li, Z., Zhao, Y., Shen, B., Huang, X., Zhu, H., Orkin, S., and Shen, X. (2015) Opposing Roles for the lncRNA Haunt and Its Genomic Locus in Regulating HOXA Gene Activation during Embryonic Stem Cell Differentiation. Cell Stem Cell 16, 504-516
15. Song, G.*, Hu, C.*, Zhu, H., Wang, L., Zhang, F., Li, Y., and Wu, L. (2013) New centromere autoantigens identified in systemic sclerosis using centromere protein microarrays. The Journal of Rheumatology 40, 461-468
16. Song, G.*, Hu, C.*, Zhu, H., Li, X., Zhao, L., Zhou, R., Zhang, X., Zhang, F., Wu, L., and Li, Y. (2013) Comparative proteomics study on liver mitochondria of primary biliary cirrhosis mouse model. BMC Gastroenterology 13, 64
17. Wu, L., and Song, G. (2012) Identification of new autoimmune hepatitis-specific autoantigens by using protein microarray technology. Methods in Molecular Biology 909, 227-239
18. Hu, C.*, Song, G.*, Huang, W., Liu, G., Deng, C., Zeng, H., Wang, L., Zhang, F., Zhang, X., Jeong, J., Blackshaw, S., Jiang, L., Zhu, H., Wu, L., and Li, Y. (2012) Identification of new autoantigens for primary biliary cirrhosis using human proteome microarrays. Molecular & Cellular Proteomics : MCP 11, 669-680