教育经历：
2002年9月- 2007年6月 武汉大学 博士学位
1987年9月- 1991年7月 湖北大学 学士学位
工作经历：
2007年7月至今 华中师范大学，生命科学学院，讲师，副教授
2014年3月 – 2015年3月：美国匹兹堡大学，医学院，访问学者
1991年7月- 2002年8月 武钢程潮铁矿子弟中学 教师
荣誉或奖励
2016年6月 “邻苯二甲酸酯氧化损伤机制及相关疾病的分子毒理学作用”获湖北省科学技术进步奖二等奖
2018年1月 2017年度英国皇家化学学会杰出评审专家
2018年11月 Elsevier优秀评审专家（Ecotoxicology and Environmental Safety）
2019年7月 第四届全国大学生生命科学创新创业大赛指导教师一等奖
2021年12月 “空气污染健康影响监测与风险评估技术及应用”获2021年中华预防医学会科学技术奖二等奖
2013年度、2014年度、2015年度、2016年度、2017年度、2018年度、2019年度、2020年度履职考核优秀
主要研究领域：
邻苯二甲酸酯、甲醛、塑料微粒等环境污染物对人体健康的影响；温湿度和化学污染物对健康影响的协同作用；环境分子毒理学
承担科研项目：
1. 国家重点研发计划 "建筑室内空气质量运维共性关键技术研究"（课题编号：2017YFC0702704）子课题，2017年7月-2020年7月，主持
2. 国家重点研发计划委托课题，"基于热舒适评价的人体生理参数指标测试研究"， 2017年6月-2018年6月，主持
3.中央高校科研业务费2020年探索创新项目，CCNU20TS020，邻苯二甲酸二异壬酯暴露与特应性疾病进程研究，主持
4.中央高校科研业务费2017年重大交叉研究项目，CCNU17ZDJC05，建筑室内过敏性疾病的健康风险和致病机理研究，主持
5. 国家自然科学基金青年项目（21507026）：增塑剂邻苯二甲酸酯对大鼠甲状腺内分泌干扰作用及其机理的研究，2016.1-2018.12, 参加。
6. 国家科技支撑计划子课题（2012BAJ02B03）：建筑室内半挥发有机物（SVOC）及其复合污染检测及控制关键技术研究，2012.1-2016.12，参加
7. 国家科技支撑计划（2012BAJ02B06，建筑室内空气污染监测及运营管理技术研究）子课题：不同典型污染物浓度水平下的动物实验研究，2015.9-2016.10，主持
8. 国家科技支撑计划（2012 BAJ02B05-1，西部内陆地区室内环境对人体健康的影响及评估）子课题：实验室环境中不同温湿度及污染物浓度条件下的动物实验测试，2015.1-2015.12，主持
9. 国家自然科学基金面上项目（51076079）：室内典型SVOC散发、传播机理及体内暴露研究，2011.1-2013.12，参加。
10. 湖北省自然科学基金（2008CBD107）： EV71病毒衣壳蛋白与宿主细胞内源蛋白相互作用研究，2009.1-2010.12, 主持。
代表性论文（*表示通讯作者）：
1、Zhaolan Wei, Yunyi Wang, Shuwei Wang, Jing Xie, Qi Han, Mingqing Chen*, Comparing the effects of polystyrene microplastics exposure on reproduction and fertility in male and female mice, Toxicology, 2022, 465, 153059, https://doi.org/10.1016/j.tox.2021.153059.
2、Jing Xie, Qi Han, Zhaolan Wei, Yunyi Wang, Shuwei Wang, Mingqing Chen*， Phenanthrene induces autism-like behavior by promoting oxidative stress and mTOR pathway activation, Toxicology, 2021, 461,152910.
3、Wei Qin, Jiufei Duan, Xiaoman Xie, Jun Kang, Ting Deng, Mingqing Chen*, Exposure to diisononyl phthalate promotes atopic march by activating of NF-κB and p38 MAPK, Toxicology and Applied Pharmacology, 2020，395, 114981.
4、Jiufei Duan, Jing Xie, Ting Deng, Xiaoman Xie, Hong Liu, Baizhan Li, Mingqing Chen*, Exposure to both formaldehyde and high relative humidity exacerbates allergic asthma by activating the TRPV4-p38 MAPK pathway in Balb/c mice, Environmental Pollution, 2020, 256: 113375.
5、Xiaoman Xie#, Ting Deng#, Jiufei Duan, Jing Xie, Junlin Yuan, Mingqing Chen*, Exposure to polystyrene microplastics causes reproductive toxicity through oxidative stress and activation of the p38 MAPK signaling pathway, Ecotoxicology and Environmental Safety, 2020,190: 110133（高被引论文ESI 1%）
6、Yuxin Wu #, Jiufei Duan, #, Baizhan Li, Hong Liu*, Mingqing Chen*, Exposure to formaldehyde at low temperatures aggravates allergic asthma involved in transient receptor potential ion channel，Environmental Toxicology and Pharmacology，2020,80:103469
7、Ting Deng#, Xiaoman Xie#, Jiufei Duan, Mingqing Chen*, Di-(2-ethylhexyl) phthalate induced an increase in blood pressure via activation of ACE and inhibition of the bradykinin-NO pathway, Environmental Pollution, 2019, 247: 927-934.
8、Ting Deng, Xiaoman Xie, Jiufei Duan, Mingqing Chen*, Exposure to diisononyl phthalate induced an increase in blood pressure through activation of the ACE/ AT1R axis and inhibition of NO production, Toxicology Letters, 2019, 309: 42-50
9、Xiaoman Xie#, Ting Deng#, Jiufei Duan, Shumao Ding, Junlin Yuan*, Mingqing Chen*, Comparing the effects of diethylhexyl phthalate and dibutyl phthalate exposure on hypertension in mice, Ecotoxicology and Environmental Safety, 2019,174:75-82
10、Jiufei Duan; Ting Deng; Jun Kang; Mingqing Chen*, DINP aggravates autoimmune thyroid disease through activation of the Akt/mTOR pathway and suppression of autophagy in Wistar rats, Environmental Pollution, 2019，245：316-324
11、Shuzhen Ge, Biao Yan, Jiawei Huang, Yingying Chen, Mingqing Chen, Xu Yang, Yang Wu, Dingwen Shen, Ping Ma, Diisodecyl phthalate aggravates the formaldehyde-exposure-induced learning and memory impairment in mice, Food and Chemical Toxicology, 2019, 152-161
12、Jiufei Duan, Jun Kang, Ting Deng, Xu Yang, Mingqing Chen*. Exposure to DBP and high iodine aggravates autoimmune thyroid disease through increasing the levels of IL-17 and thyroid-binding globulin in Wistar rats. Toxicological Sciences, 2018, 163(1):196-205.
13、Jun Kang#, Jiufei Duan#, Jing Song, Chen Luo, Hong Liu, Baizhan Li, Xu Yang, Wei Yu*, Mingqing Chen*, Exposure to a Combination of Formaldehyde and DINP Aggravated Asthma-like Pathology through Oxidative Stress and NF-κB activation. Toxicology, 2018, 404–405: 49–58
14、Ting Deng, Yu Zhang, Yang Wu, Ping Ma, Jiufei Duan, Wei Qin, Xu Yang, Mingqing Chen*, Dibutyl phthalate exposure aggravates type 2 diabetes by disrupting the insulin-mediated PI3K/AKT signaling pathway, Toxicology Letters, 2018, 290, 1-9.
15、Jiufei Duan#, Jun Kang#, Wei Qin, Ting Deng, Hong Liu, Baizhan Li, Wei Yu, Siyin Gong, Xu Yang, Mingqing Chen*, Exposure to formaldehyde and diisononyl phthalate exacerbate Neuroinflammation through NF-κB activation in a mouse asthma model. Ecotoxicology and Environmental Safety, 2018, 163:356-364.
16、Wei Qin, Ting Deng, Haiyan Cui, Qian Zhang, Xudong Liu, Xu Yang, Mingqing Chen*. Exposure to diisodecyl phthalate exacerbated Th2 and Th17-mediated asthma through aggravating oxidative stress and the activation of p38 MAPK. Food and Chemical Toxicology, 2018, 114:78-87
17、Chenqiu Du#, Jun Kang#, Wei Yu*, Mingqing Chen, Baizhan Li, Hong Liu, Han Wang. Repeated exposure to temperature variation exacerbates airway inflammation through TRPA1 in a mouse model of asthma, Respirology, 2019, 24(3):238-245. （Editorial推荐）
18、Shiping Shen#, Jinquan Li#, Huihui You, Zhuo Wu, Yang Wu, Yun Zhao, Yuqing Zhu, Qing Guo, Xiaoxiao Li, Rui Li, Ping Ma, Xu Yang, Mingqing Chen*, Oral exposure to diisodecyl phthalate aggravates allergic dermatitis by oxidative stress and enhancement of thymic stromal lymphopoietin, Food and Chemical Toxicology, 2017, 99: 60-69
19、Jun Kang, Yong Ding, Baizhan Li, Hong Liu, Xu Yang and Mingqing Chen*, TRPA1 mediated aggravation of allergic contact dermatitis induced by DINP and regulated by NF-κB activation. 2017, Sci.Rep.7, 43586; doi: 10.1038/srep43586.
20、Yang Wu, Jinquan Li, Biao Yan, Yuqing Zhu, Xudong Liu, Mingqing Chen, Dai Li, Ching-Chang Lee, Xu Yang & Ping Ma. Oral exposure to dibutyl phthalate exacerbates chronic lymphocytic thyroiditis through oxidative stress in female Wistar rats. 2017, Sci.Rep.7: 15469 DOI:10.1038/s41598-017-15533-z
21、Biao Yan#，Jinquan Li#, Junhui Guo#, Ping Ma, Zhuo Wu, ZhenHao Ling, Hai Guo, Yoshino Hiroshi, U. Yanagi, Xu Yang, Shengwei Zhu*, Mingqing Chen*，The toxic effects of indoor atmospheric fine particulate matter collected from allergic and non-allergic families in Wuhan on mouse peritoneal macrophages. Journal of Applied Toxicology，2016，36（4）：596-608
22、Jun Kang, Jing Song, Shiping Shen, Baizhan Li, Xu Yang, Mingqing Chen*.Diisononyl phthalate aggravates allergic dermatitis by activation of NF-κB, 2016. Oncotarget, 7(51): 85472-85482.
23、Mingqing Chen#, Fan Sun#, Lei Han#, Zhaoxiao Qu,. 2016. Kaposi's sarcoma herpesvirus (KSHV) microRNA K12-1 functions as an oncogene by activating NF-κB/IL-6/STAT3 signaling. Oncotarget, 7(22), 33363-33373.
24、Shengwei Zhu* ，Wei Cai，Hiroshi Yoshino，U. Yanagi，Kenichi Hasegawa，Naoki Kagi，Mingqing Chen，Primary pollutants in schoolchildren's homes in Wuhan, China，Building and Environment，2015，93：41-53
25、Anna Min，Fengming Liu，Xu Yang，Mingqing Chen*，Benzyl butyl phthalate exposure impairs learning and memory and attenuates neurotransmission and CREB phosphorylation in mice，Food and Chemical Toxicology，2014，71：81-89
26、Qiang Zeng, Chenxi Wei, Yang Wu, Ke Li, Shumao Ding, Junlin Yuan, Xu Yang, Mingqing Chen*. Approach to distribution and accumulation of dibutyl phthalate in rats by immunoassay，Food and Chemical Toxicology，2013，56：18-27
27、Mingqing Chen, Hongbo Wei, Junwei Cao, Ruijie Liu, Youliang Wang, Congyi Zhen. 2007. Expression of Bacillus subtilis proBA genes and reduction of feedback inhibition of proline synthesis increases proline production and confers osmotolerance in transgenic Arabidopsis. Journal of Biochemistry and Molecular Biology, 40: 396-403.
28、Mingqing Chen, Junwei Cao, Congyi Zhen, Qing Liu.2006. Directed evolution of an artificial bifunctional enzyme, γ-glutamyl kinase/γ-glutamyl phosphate reductase, for improved osmotic tolerance of Escherichia coli transformants. FEMS Microbiology Letters, 263: 41-47.
学术兼职
1、担任中国环境科学学会室内环境与健康分会委员
2、担任Environmental Science & Technology, Allergy, Journal of Hazardous Materials，Environment International，Science of the Total Environment，Environmental Pollution, Food and Chemical Toxicology, Ecotoxicology and Environmental Safety, Toxicological Sciences, Building and Environment，Journal of Biological Chemistry, Toxicology， American Journal of Respiratory，International Journal of Nanomedicine，Molecular and Cellular Endocrinology, Environmental Toxicology and Pharmacology，Journal of Applied Toxicology，Scientific Reports, Toxicology Research等二十余种刊物评审专家。
