副教授

  • 姓名:汪家林
  • 职称:副教授
  • 研究领域:1. 昆虫先天免疫的激素调控机制2.昆虫生殖的激素调控机制
  • 联系方式:jlwang(AT)mail.ccnu.edu.cn
  • 办公室地址:5307
  • 更多信息:


教育经历:

200409- 200906 山东大学 博士

200009- 200406 安徽师范大学 学士

 

工作经历:

201207- 至今 华中师范大学 副教授

201908- 202001 加州大学河滨分校 访问学者

   201509- 201610 加州大学河滨分校 访问学者

201203- 201209 香港大学 研究助理

200907- 201206 华中师范大学 讲师

 

主要研究领域:

1. 昆虫内分泌与先天免疫的互作机制

2. 昆虫生殖的内分泌调控机制

3. 害虫的生物防治

 

承担科研项目:

1. 国家自然科学基金面上项目(31872301):模式识别蛋白介导20E信号调控棉铃虫血细胞包囊的分子机理,2019.01-2022.12,主持。

2. 国家自然科学基金青年项目(31101672):棉铃虫应答20E调控体液免疫相关分子的鉴定和功能研究,2012.01-2014.12,主持。

3. 湖北省青年科技晨光计划(鄂科协办[2018]79):蚊虫生殖控制技术与策略,主持。

4. 湖北省自然科学基金面上项目(2016CFB560)C型凝集素在棉铃虫抵御中华卵索线虫感染过程中的功能研究,2016.01-2017.12,主持。

5. 湖北省自然科学基金面上项目(2010CDB01204):基于蜕皮激素对昆虫体液免疫的调控寻找杀虫新靶标,2010.01-2011.12,主持。

6. 中央高校基本科研业务费探索创新类(CCNU19TS026):β-integrin介导棉铃虫血细胞包囊的分子机理,2019.04-2020.04,主持。

7. 中央高校基本科研业务费探索创新类(CCNU14A02013):棉铃虫C型凝集素3基因表达调控的分子基础,2014.01-2015.12,主持。

8. 遗传调控与整合生物学湖北省重点实验室开放课题(GRIB201702)20-羟基蜕皮酮调控棉铃虫血细胞包囊的分子机理,2017.01-2018.12,主持。

9. 国家自然科学基金面上项目(31672352)Wolbachia对果蝇雄性生殖系统先天免疫的影响及其与生殖的关系,2017.01-2020.12,参加。

 

代表性论文:

1、Wang GJ, Wang WW, Liu Y, Chai LQ, Wang GX, Liu XS, Wang YF, Wang JL*. 2021. Steroid hormone 20-hydroxyecdysone promotes CTL1-mediated cellular immunity in Helicoverpa armigera. Insect Science. 28:1399-1413.

2、Wang W, Wang G, Zhuo X, Liu Y, Tang L, Liu X, Wang J*. 2020. C-type lectin-mediated microbial homeostasis is critical for Helicoverpa armigera larval growth and development. PLoS Pathogens. 16:e1008901.

3、Lin Z#, Wang JL#, Cheng Y, Wang JX, Zou Z*. 2020. Pattern recognition receptors from lepidopteran insects and their biological functions. Developmental and Comparative Immunology. 108:103688.

4、Wang GJ, Zhuo XR, Wang WW, Liu XS, Wang GX, Wang JL*. 2019. Molecular characterization of immune responses of Helicoverpa armigera to infection with the mermithid nematode Ovomermis sinensis. BMC Genomics. 20:161.

5、Zhuo XR, Chen L, Wang GJ, Liu XS, Wang YF, Liu K, Yu XQ, Wang JL*. 2018. 20-Hydroxyecdysone promotes release of GBP-binding protein from oenocytoids to suppress hemocytic encapsulation. Insect Biochemistry and Molecular Biology. 92:53-64. (受邀为ATLAS of Science撰写layman¢s summaryhttp://atlasofscience.org/ecdysone-induces-a-termination-of-encapsulation-via-gbp-gbpb-interaction/).

6、Wang P#, Zhuo XR#, Tang L, Liu XS, Wang YF, Wang GX, Yu XQ, Wang JL*. 2017. C-type lectin interacting with β-integrin enhances hemocytic encapsulation in the cotton bollworm, Helicoverpa armigera. Insect Biochemistry and Molecular Biology. 86: 29-40.

7、Wang JL, Saha TT, Zhang Y, Zhang C, Raikhel AS*. 2017. Juvenile hormone and its receptor methoprene-tolerant promote ribosomal biogenesis and vitellogenesis in the Aedes aegypti mosquito. Journal of Biological Chemistry. 292: 10306-10315.

8、Li J, Song CX, Li YP, Li L, Wei XH, Wang JL*, Liu XS*. 2015. Rab3 is involved in cellular immune responses of the cotton bollworm, Helicoverpa armigera. Developmental and Comparative Immunology, 50: 78-86.

9、Wang JL, Chen L, Tang L, Zhao HB, Liu XS*, Wang YF*. 2014. 20-hydroxyecdysone transcriptionally regulates humoral immunity in the fat body of Helicoverpa armigera. Insect Molecular Biology, 23: 842-856.

10、Liu C#, Wang JL#, Zheng Y, Xiong EJ, Li JJ, Yuan LL, Yu XQ, Wang YF*. 2014. Wolbachia-induced paternal defect in Drosophila is likely by interaction with the juvenile hormone pathway. Insect Biochemistry and Molecular Biology, 49: 49-58.

11、Wang JL*, Zhang Q, Tang L, Chen L, Liu XS, Wang YF*. 2014. Involvement of a pattern recognition receptor C-type lectin 7 in enhancing cellular encapsulation and melanization due to its carboxyl-terminal CRD domain in the cotton bollworm, Helicoverpa armigera. Developmental and Comparative Immunology, 44: 21-29.

12、Wang JL*, Liu XS, Zhang Q, Zhao HB, Wang YF*. 2012. Expression profiles of six novel C-type lectins in response to bacterial and 20E injection in the cotton bollworm (Helicoverpa armigera). Developmental and Comparative Immunology, 37: 221-232.

13、Zheng Y#, Wang JL#, Liu C, Wang CP, Walker T, Wang YF*. 2011. Differentially expressed profiles in the larval testes of Wolbachia infected and uninfected Drosophila. BMC Genomics, 12:595.

14、Wang JL, Wang LF, Wang JX, Zhao XF*. 2010. The expression patterns of a eukaryotic initiation factor 3 subunit H in the silk glands in Bombyx mori. Archives of Insect Biochemistry and Physiology, 75: 1-12.

15、Wang JL, Zhang YP, Gu YY, Wang JX, Zhao XF*. 2009. Function of a TGF-β inducible nuclear protein in the silk gland in Bombyx mori. Insect Molecular Biology, 18: 243-251.

16、Wang JL, Wang JX, Zhao XF*. 2008. Molecular cloning and expression profiles of the acyl-CoA-binding protein gene from the cotton bollworm Helicoverpa armigera. Archives of Insect Biochemistry and Physiology, 68: 79-88.

17、Wang JL, Jiang XJ, Wang Q, Hou LJ, Xu DW, Wang JX, Zhao XF*. 2007. Identification and expression profile of a putative basement membrane protein gene in the midgut of Helicoverpa armigera. BMC Developmental Biology, 7:76.

 

社会兼职:

湖北省昆虫学会理事(2018.10-

 

---------------------------------------

英文版:

Jialin Wang

Title

Associate Professor

 

Office Address

5307

Lab Address

5306

E-mail

jlwang@mail.ccnu.edu.cn

Resume:

Jul.2012 - present: Associate Professor, Central China Normal University, Wuhan, China

Aug.2019 - Jan.2020: Visiting Scholar, University of California, Riverside, California, USA

Sep.2015 - Oct.2016: Visiting Scholar, University of California, Riverside, California, USA

Mar.2012 - Sep.2012: Research Assistant, The University of Hong Kong, Hong Kong, China

Jul.2009 - Jun.2012: Assistant Professor, Central China Normal University, Wuhan, China

Sep.2004 - Jun.2009: Ph.D. in Biochemistry and Molecular Biology, Shandong University, Jinan, China

Sep. 2000 - Jun.2004: B. Sc. in Biology, Anhui Normal University, Wuhu, China.

 

Research Interestes:

1. Interaction mechanisms between endocrine and innate immunity

2. Endocrine regulation of insect reproduction

3. Biological control of insect pests

Research Grants

1. National Natural Science Foundation of China (no.31872301, 2019.01-2022.12): Molecular mechanisms for 20E signal regulation of hemocytic encapsulation mediated by pattern recognition proteins in Helicoverpa armigera.

2. National Natural Science Foundation of China (no.31101672, 2012.1-2014.12): Identification and functional analyses of immune-related genes in response to 20E treatment in the cotton bollworm (Helicoverpa armigera).

3. Natural Science Foundation of Hubei Province (2016CFB560, 2016.01-2017.12): Functional analyses of Helicoverpa armigera C-type lectins involved in defending against parasitism by Ovomermis sinensis.

4. Natural Science Foundation of Hubei Province (2010CDB01204, 2010.01-2011.12): Searching novel targets of insecticide based on 20E regulation of insect humoral immunity.

Representative Peer-reviewed Publications:

1. Wang GJ, Wang WW, Liu Y, Chai LQ, Wang GX, Liu XS, Wang YF, Wang JL*. 2021. Steroid hormone 20-hydroxyecdysone promotes CTL1-mediated cellular immunity in Helicoverpa armigera. Insect Science. 28:1399-1413.

2. Wang W, Wang G, Zhuo X, Liu Y, Tang L, Liu X, Wang J*. 2020. C-type lectin-mediated microbial homeostasis is critical for Helicoverpa armigera larval growth and development. PLoS Pathogens. 16:e1008901.

3. Lin Z#, Wang JL#, Cheng Y, Wang JX, Zou Z*. 2020. Pattern recognition receptors from lepidopteran insects and their biological functions. Developmental and Comparative Immunology. 108:103688.

4. Wang GJ, Zhuo XR, Wang WW, Liu XS, Wang GX, Wang JL*. 2019. Molecular characterization of immune responses of Helicoverpa armigera to infection with the mermithid nematode Ovomermis sinensis. BMC Genomics. 20:161.

5. Zhuo XR, Chen L, Wang GJ, Liu XS, Wang YF, Liu K, Yu XQ, Wang JL*. 2018. 20-Hydroxyecdysone promotes release of GBP-binding protein from oenocytoids to suppress hemocytic encapsulation. Insect Biochemistry and Molecular Biology. 92:53-64.

(Invited to prepare a layman¢s summary for ATLAS of Sciencehttp://atlasofscience.org/ecdysone-induces-a-termination-of-encapsulation-via-gbp-gbpb-interaction/).

6. Wang P#, Zhuo XR#, Tang L, Liu XS, Wang YF, Wang GX, Yu XQ, Wang JL*. 2017. C-type lectin interacting with β-integrin enhances hemocytic encapsulation in the cotton bollworm, Helicoverpa armigera. Insect Biochemistry and Molecular Biology. 86: 29-40.

7. Wang JL, Saha TT, Zhang Y, Zhang C, Raikhel AS*. 2017. Juvenile hormone and its receptor methoprene-tolerant promote ribosomal biogenesis and vitellogenesis in the Aedes aegypti mosquito. Journal of Biological Chemistry. 292: 10306-10315.

8. Li J, Song CX, Li YP, Li L, Wei XH, Wang JL*, Liu XS*. 2015. Rab3 is involved in cellular immune responses of the cotton bollworm, Helicoverpa armigera. Developmental and Comparative Immunology, 50: 78-86.

9. Wang JL, Chen L, Tang L, Zhao HB, Liu XS*, Wang YF*. 2014. 20-hydroxyecdysone transcriptionally regulates humoral immunity in the fat body of Helicoverpa armigera. Insect Molecular Biology, 23: 842-856.

10. Liu C#, Wang JL#, Zheng Y, Xiong EJ, Li JJ, Yuan LL, Yu XQ, Wang YF*. 2014. Wolbachia-induced paternal defect in Drosophila is likely by interaction with the juvenile hormone pathway. Insect Biochemistry and Molecular Biology, 49: 49-58.

11. Wang JL*, Zhang Q, Tang L, Chen L, Liu XS, Wang YF*. 2014. Involvement of a pattern recognition receptor C-type lectin 7 in enhancing cellular encapsulation and melanization due to its carboxyl-terminal CRD domain in the cotton bollworm, Helicoverpa armigera. Developmental and Comparative Immunology, 44: 21-29.

12. Wang JL*, Liu XS, Zhang Q, Zhao HB, Wang YF*. 2012. Expression profiles of six novel C-type lectins in response to bacterial and 20E injection in the cotton bollworm (Helicoverpa armigera). Developmental and Comparative Immunology, 37: 221-232.

13. Zheng Y#, Wang JL#, Liu C, Wang CP, Walker T, Wang YF*. 2011. Differentially expressed profiles in the larval testes of Wolbachia infected and uninfected Drosophila. BMC Genomics, 12:595.

14. Wang JL, Wang LF, Wang JX, Zhao XF*. 2010. The expression patterns of a eukaryotic initiation factor 3 subunit H in the silk glands in Bombyx mori. Archives of Insect Biochemistry and Physiology, 75: 1-12.

15. Wang JL, Zhang YP, Gu YY, Wang JX, Zhao XF*. 2009. Function of a TGF-β inducible nuclear protein in the silk gland in Bombyx mori. Insect Molecular Biology, 18: 243-251.

16. Wang JL, Wang JX, Zhao XF*. 2008. Molecular cloning and expression profiles of the acyl-CoA-binding protein gene from the cotton bollworm Helicoverpa armigera. Archives of Insect Biochemistry and Physiology, 68: 79-88.

17. Wang JL, Jiang XJ, Wang Q, Hou LJ, Xu DW, Wang JX, Zhao XF*. 2007. Identification and expression profile of a putative basement membrane protein gene in the midgut of Helicoverpa armigera. BMC Developmental Biology, 7:76.