教育经历
2014.01-2017.02 香港浸会大学 化学生物学 博士
2010.09-2012.07 武汉大学 化学 硕士
2006.09-2010.07 安徽师范大学 化学 学士
工作经历
2021.12-今 华中师范大学 生命科学学院 研究员
2020.01-2021.10 香港理工大学 应用生物及化学科技学系 研究助理教授
2017.11-2019.09 帝国理工学院 化学系 访学
学术奖励
2021年湖北省高层次人才支持计划（创新）项目
2020年教育部高等学校科学研究优秀成果奖（科学技术）二等奖
2019年香港科学会青年科学家奖（生命科学领域）（Young Scientist Award in Life Science）
主要研究领域
蛋白靶向性功能分子的设计与构建
智能响应型生物探针的开发
肿瘤成像和治疗应用
招生
本课题组热忱欢迎有化学生物学、医学、药学等背景的同学加入。
代表性论文
1. H.-F. Chau, Y. Wu, W.-Y. Fok, W. Thor, W. C.-S. Cho, P. Ma, J. Lin, N.-K. Mak, J.-C. G. Bunzli*, L. Jiang*, N. J. Long*, H. L. Lung, K.-L. Wong*, Lanthanide-based peptide-directed visible/near-infrared imaging and inhibition of LMP1, JACSAu, 1 (2021), 1034-1043.
2. L. Jiang, H.-N. Mak, E. RH Walter, W.-T. Wong*, K.-L. Wong*, N. J. Long*, A fluorescent probe for the discrimination of oxidation states of palladium, Chemical Science, 12 (2021), 9977-9982.
3. (contributed equally) T. Clough#, L. Jiang#, K.-L. Wong*, N. J. Long*, Ligand design strategies to increase stability of gadolinium-based MRI contrast agents, Nature Communications, 10 (2019), 1420.
4. L. Jiang, H. L. Lung*, T. Huang, R. Lan, S. Zha, L. S. Chan, W. Thor, T.-H. Tsoi, H. Chau, C. Boreström, S. Cobb, S. W. Tsao, G.-L. Law*, W.-T. Wong, W. C.-S. Tai, W. Y. Chau, Y. Du, A. K. S. Chiang, J. M. Middeldorp, N.-K. Mak*, N. J. Long*, K.-L. Wong*, Reactivation of Epstein Barr virus by a dual-responsive fluorescent EBNA1-targeting agent with zinc-chelating function, PNAS, 116 (2019), 26614.
5. L. Jiang, C. Xie, H. L. Lung, K. W. Lo*, G.-L. Law*, N.-K. Mak*, K.-L. Wong*, EBNA1-targeted inhibitors: Novel approaches for the treatment of Epstein-Barr virus-associated cancers, Theranostics, 8 (2018), 5307-5319.
6. L. Jiang, R. Lan, T. Huang, C.-F. Chan, H. Li, S. Lear, J. Zong, W.-Y. Wong, M. M.-L. Lee, B. D. Chan, W.-L. Chan, W.-S. Lo, N.-K. Mak*, M. L. Lung, H. L. Lung, S. W. Tsao, G. S. Taylor, Z.-X. Bian, W. C. S. Tai, G.-L. Law*, W.-T. Wong*, S. L. Cobb* and K.-L. Wong*, EBNA1-targeted probe for the imaging and growth inhibition of tumours associated with the Epstein-Barr virus, Nature Biomedical Engineering, 1 (2017), 0042.
(highlighted by Nature Biomedical Engineering and Cell Chemical Biology)
7. L. Jiang, Y.-L. Lau, H. Li, C.-F. Chan, R. Lan, W.-L. Chan, T. C.-K. Lau, G. S.-W. Tsao, N.-K. Mak* and K.-L. Wong*, EBNA1-specific luminescent small molecules for the imaging and inhibition of latently EBV-infected tumor cells, Chemical Communications, 50 (2014), 6517-6519.
专利
1. K.-L. Wong, N.-K. Mak, L. Jiang, Therapeutic inhibitor for EBV-associated tumor with tailor responsive optical imaging. 美国专利, 专利号：US 10,137,115 B2.
2. K.-L. Wong, N.-K. Mak, L. Jiang, Zinc-binder based EBNA1-specific compounds. 美国专利，专利号：US 11,046,731 B2.
