电话/ 传真:027-67867229
电 子邮 件:chenqc@mail.ccnu.edu.cn
通 讯地 址:武汉市珞瑜路152号,华中师范大学生命科学学院,邮编:430079
研究组负责人:陈其才
研究组成员:陈其才、罗峰、廖晓梅、王少辉、王欣、唐佳、付子英
研究组简介(不超过200字):脑科学与认知科学是国际竞争的战略性研究领域,阐明脑的结构与功能,成为21世纪重大挑战之一。本研究组主要从分子、细胞和回路水平开展感觉功能调控与整合,以及学习与记忆机制方面的研究,试图了解信息怎样编码、储存并修饰,以及怎样做出抉择以指导行为等。我国患有听力障碍的患者数目惊人;老年性的学习与记忆、认知障碍也日趋突出,因此,开展这方面的研究既可在基础理论方面获得新的认识,也可为相关疾病的临床治疗提供基础理论依据。
近期的部分成果:
[1] Mei Hui-Xian, Cheng Liang, Chen* Qi-Cai: Neural interactions in unilateral colliculus and between bilateral colliculi modulate auditory signal processing.Front Neural Circuits7(Article 68): 1~8, 2013
[2] Feng Luo and Jun Yan:Sound-speci?c plasticity in the primary auditory cortex as induced by the cholinergic pedunculopontine tegmental nucleus.Eur J Neurosci37: 393–399, 2013
[3] Cheng Liang,Mei Hui-Xian, Tang Jia, Fu Zi-Ying, Jen Philip H.-S., Chen Qi-Cai: Bilateral collicular interaction: modulation of auditory signal processing in frequency domain.Neurosci235:27-39,2013
[4] Cheng L, Wang SH, Jia N, Xie M and Liao XM: Environmental situation influences the cognition of developing mice by inducing changes in oxidative and apoptosis status.Brain&Dev, 2013, in press (http://dx.doi.org /10.1016/ j.braindev. 2012.11.015)
[5] Mei Hui-Xian,Cheng Liang,Jia Tang, Zi-Ying Fu, Philip H.-S. Jen, Qi-Cai Chen*: Bilateral collicular interaction: modulation of auditory signal processing in amplitude domain.PLoS One7(7): e-4131-11, 2012
[6] Wang SH, Liao XM, LiuD, Hu JU, Yin YY, Wang JZ, Zhu LQ: NGF Promotes long-term memory formation by activating poly (ADF-ribose) polymerase-1.Neuropharmacol63:1085-1092, 2012
[7] Cheng Liang, Wang Shao-Hui, Chen Qi-Cai and Liao Xiao-Mei :Moderate noise induced cognition impairment of mice and its underlying mechanisms.Physiol & Behav104(5): 981-988, 2011
[8] Feng Luo, Xiuping Liu, Carol Wang, and Jun Yan:The Pedunculopontine Tegmental Nucleus: A Second Cholinergic Source for Frequency-Specific Auditory Plasticity.J Neurophysiol105(1):107-116, 2011
[9] TANG Jia, FU Ziying, JEN Philip H.-S. and CHEN Qicai:Recovery cycle of single-on and double-on neurons in inferior colliculus of CF-FM bat,Hipposideros armiger.Brain Res1385: 114-126,2011
[10] Zi-Ying FU, Jia TANG, Philip Hung-Sun JEN and Qi-Cai CHEN: The auditory response properties of single-on and double-on responders in the inferior colliculus of the leaf-nosed bat,Hipposideros armiger.Brain Res1306:39-52, 2010
[11] Feng Luo, Qianzhou Wang, Alireza Kashani, and Jun Yan: Corticofugal modulation of initial sound processing in the brain.J Neurosci28(45): 11615-11621, 2008
[12] Xin Wang, Feng Luo, Feijian Wu, Qicai Chen and Philip H.-S. Jen: The recovery cycle of bat duration-selective collicular neurons varies with hunting phase.Neuroreport19(8):861-865, 2008